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Caffeine dose

The caffeine dose that research shows helps endurance, for your weight, and the safe limits.

Your numbers

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Caffeine doseFondoLab

216–432

mg

Lowest dose
144 mg
Most at once
200 mg
Most a day
400 mg

216–432 mg is the range shown to help endurance: 3 to 6 mg per kg. Start at the low end, and try it in training first.

Most studies take it about 60 minutes before the start. In a long race, a dose later on, closer to fatigue, may help more. Try your dose and timing in training.

Even your low dose is above 200 mg, the safe single dose: split it, for example half before the start and half later in the race.

The top of your range is above 400 mg, the most EFSA considers safe in a day for healthy adults. Stay under it.

How we got this

The formula with your numbers in it, then every constant we used and where it comes from.

The working

  1. 3 to 6 mg/kg × 72 kg = 216 to 432 mg

The numbers and their sources

A number marked FondoLab default is our judgement, not a study's finding; we say so rather than borrow authority.

NumberValueBasis
Caffeine dose 6.0 / 4.5 / 3.0 mg/kg (low / medium / high sensitivity) 3–6 mg/kg reliably improves endurance performance; very high doses bring side effects without more benefit. [1]
Caffeine caps 200 mg per dose, 400 mg per ride EFSA considers single doses up to 200 mg, and up to 400 mg a day, safe for healthy adults, including during intense exercise. Each dose is capped first, so a heavier or less caffeine-sensitive rider can get less in total than their dose by body weight; the plan says when that happens. [2]
Caffeine timing early dose ~45 min before the start; finishing dose 75 min before the finish on rides of 3h or more Blood levels peak 30–120 min after swallowing and the half-life is 4–6 h. Caffeine taken later in long events may help more than caffeine taken before the start. The exact 45 and 75 minutes are FondoLab defaults. [1]

References

  1. Guest NS, VanDusseldorp TA, Nelson MT, et al. (2021). International society of sports nutrition position stand: caffeine and exercise performance. Journal of the International Society of Sports Nutrition 18:1. doi:10.1186/s12970-020-00383-4

    Position stand · Synthesis of studies in trained and untrained people across many sports; aerobic endurance shows the most consistent benefit. · Read by us: Full text, first third (open access)

    Caffeine reliably improves endurance performance, with moderate to large benefits, though the size of the effect differs between people.

    • Effective dose: 3–6 mg per kg of body weight. The minimum effective dose may be as low as 2 mg/kg.
    • Very high doses, around 9 mg/kg, bring many side effects and are not needed for a benefit.
    • The most common timing is 60 min before exercise. Blood levels peak 30–120 min after swallowing it; the half-life is 4–6 h.
    • Caffeine gum is absorbed through the cheek and acts faster than capsules.
    • In long events, caffeine taken later in the race, closer to fatigue, may help more than caffeine taken before the start; low doses taken late compared well with higher doses taken an hour before.
    • Responses vary, so riders should try their dosing and timing in training.
  2. EFSA Panel on Dietetic Products, Nutrition and Allergies (2015). Scientific Opinion on the safety of caffeine. EFSA Journal 13(5):4102. doi:10.2903/j.efsa.2015.4102

    Regulatory scientific opinion · Healthy adults in the EU, from all dietary sources. Separate limits apply in pregnancy and for children. · Read by us: Summary (EUFIC); the opinion itself was not reachable. Read it before relying on more than the points below.

    For healthy adults:

    • Single doses up to 200 mg raise no safety concerns.
    • Up to 400 mg over 24 hours is unlikely to cause harm.
    • Both levels also hold for healthy adults doing intense physical exercise.

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